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CCR8 蛋白

CCR8 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491570
发货至: 中国
  • 抗原 See all CCR8 蛋白
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    蛋白类型
    Synthetic
    宿主
    • 9
    • 2
    • 2
    资源
    • 8
    • 2
    • 2
    • 1
    HEK-293 Cells
    原理
    Human CCR8 full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product CCR8 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    别名
    CCR8 (CCR8 产品)
    别名
    CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein
    背景
    CC-CKR-8,CCR-8,CDw198,CKRL1,CMKBR8,CMKBRL2,CY6,GPRCY6,
    Description: TER1A member of the beta chemokine receptor family,which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309,thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically,this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
    分子量
    The human full length CCR8 Protein has a MW of 40.7 kDa
    UniProt
    P51685
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