GPR75 蛋白
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- 抗原 See all GPR75 蛋白
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- 蛋白类型
- Synthetic
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human GPR75 full length protein-synthetic nanodisc
- 产品特性
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR75 蛋白
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- 应用备注
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- 说明
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- 别名
- GPR75 (GPR75 产品)
- 别名
- GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein
- 背景
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GPRchr2,
Description: WI31133G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. - 分子量
- The human full length GPR75 protein has a MW of 59.4 kDa
- UniProt
- O95800
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