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GPR75 蛋白

GPR75 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491667
发货至: 中国
  • 抗原 See all GPR75 蛋白
    GPR75 (G Protein-Coupled Receptor 75 (GPR75))
    蛋白类型
    Synthetic
    宿主
    • 8
    • 3
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Human GPR75 full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product GPR75 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GPR75 (G Protein-Coupled Receptor 75 (GPR75))
    别名
    GPR75 (GPR75 产品)
    别名
    GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein
    背景
    GPRchr2,
    Description: WI31133G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
    分子量
    The human full length GPR75 protein has a MW of 59.4 kDa
    UniProt
    O95800
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