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Claudin 6 Protein (CLDN6)

CLDN6 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491604
发货至: 中国
  • 抗原 See all Claudin 6 (CLDN6) 蛋白
    Claudin 6 (CLDN6)
    蛋白类型
    Synthetic
    宿主
    • 12
    • 2
    • 1
    资源
    • 9
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Human CLDN6 full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product CLDN6 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Claudin 6 (CLDN6)
    别名
    CLDN6 (CLDN6 产品)
    别名
    cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
    背景
    Claudin 6, Claudin-6, Skullin,Claudin6
    Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
    分子量
    The human full length CLDN6 Protein has a MW of 23 kDa
    UniProt
    P56747
    途径
    Hepatitis C
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