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Hepcidin Protein (Fc Tag)

HAMP 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491463
发货至: 中国
  • 抗原 See all Hepcidin (HAMP) 蛋白
    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
    蛋白类型
    Recombinant
    宿主
    • 5
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    • 3
    • 2
    • 1
    • 1
    • 1
    资源
    • 15
    • 1
    • 1
    HEK-293 Cells
    标记
    This Hepcidin protein is labelled with Fc Tag.
    原理
    Recombinant Human HAMP (65-84) Protein with C-terminal human Fc tag
    特异性
    HAMP (Ile65-Thr84) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product HAMP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
    别名
    HAMP (HAMP 产品)
    别名
    HEPC Protein, HFE2B Protein, LEAP1 Protein, PLTR Protein, Hepcidin Protein, Hamp1 Protein, Hepc Protein, Hepc1 Protein, HAMP Protein, hepcidin Protein, hamp1 Protein, hep1 Protein, hepcidin antimicrobial peptide Protein, hepcidin-like Protein, hepcidin-1 Protein, Ham percentage Protein, HAMP Protein, Hamp Protein, hamp Protein, LOC100135935 Protein, LOC106584587 Protein
    背景
    HEPC, HFE2B, LEAP1, PLTRThe product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
    分子量
    predicted molecular mass of 28.3 kDa after removal of the signal peptide. The apparent molecular mass of HAMP(65-84)-hFc is 25-35 kDa due to glycosylation.
    UniProt
    P81172
    途径
    Hormone Activity, Transition Metal Ion Homeostasis
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