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GLP1R Protein (Fc Tag)

GLP1R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491459
发货至: 中国
  • 抗原 See all GLP1R 蛋白
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 4
    • 1
    资源
    • 5
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This GLP1R protein is labelled with Fc Tag.
    原理
    Recombinant Human GLP1R Protein with C-terminal human Fc tag
    特异性
    GLP1R (Arg24-Glu139) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product GLP1R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    别名
    GLP1R (GLP1R 产品)
    别名
    GLP1R Protein, LOC100228311 Protein, GLP-1R Protein, GLP1Rc Protein, Glip Protein, RATGL1RCP Protein, glucagon like peptide 1 receptor Protein, glucagon-like peptide 1 receptor Protein, GLP1R Protein, Glp1r Protein
    背景
    GLP-1, GLP-1-R, GLP-1R
    Description: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
    分子量
    predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of GLP1R-hFc is 35-70 kDa due to glycosylation.
    UniProt
    P43220
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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