ACVR1C/ALK7 Protein (Fc Tag)
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- 抗原 See all ACVR1C/ALK7 (ACVR1C) 蛋白
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ACVR1C/ALK7 protein is labelled with Fc Tag.
- 原理
- Recombinant Human ACVR1C Protein with C-terminal human Fc tag
- 特异性
- ACVR1C (Leu22-Glu113) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ACVR1C 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- 别名
- ACVR1C (ACVR1C 产品)
- 别名
- ACVRLK7 Protein, ALK7 Protein, Alk-7 Protein, C230097P10 Protein, Alk7 Protein, habrec1 Protein, activin A receptor type 1C Protein, activin A receptor, type IC Protein, ACVR1C Protein, Acvr1c Protein
- 背景
- ACVRLK7, ALK7ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
- 分子量
- predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1C-hFc is 35-70 kDa due to glycosylation.
- UniProt
- Q8NER5
- 途径
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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