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CNTF 蛋白

CNTF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455693
发货至: 中国
  • 抗原 See all CNTF 蛋白
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    蛋白类型
    Recombinant
    宿主
    • 16
    • 9
    • 3
    • 2
    • 2
    • 2
    资源
    • 25
    • 3
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.
    产品特性
    Extracellular Domain Protein
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CNTF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    别名
    CNTF (CNTF 产品)
    别名
    GPA Protein, CNTF Protein, HCNTF Protein, AI429687 Protein, ciliary neurotrophic factor Protein, CNTF Protein, Cntf Protein
    背景
    Ciliary Neurotrophic Factor, CNTFCiliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
    分子量
    22.93 KDa
    UniProt
    P26441
    途径
    JAK/STAT Signaling
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