IL28A Protein (His tag)
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- 抗原 See all IL28A 蛋白
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL28A protein is labelled with His tag.
- 原理
- Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
- 产品特性
- Extracellular Domain Protein
- 纯度
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL28A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- 别名
- IL-28A (IL28A 产品)
- 别名
- EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein
- 背景
- Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IFNL2, IL28A, ZCYTO20IL-28A (Interferon-λ2, IFN-λ2), IL-28B/IFN-λ3, and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66 % amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96 % and 70 % aa sequence identity with human IL-28B and IL-29, respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
- 分子量
- 20.6 KDa
- UniProt
- Q8IZJ0
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