电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL28A Protein (His tag)

IL28A 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455684
发货至: 中国
  • 抗原 See all IL28A 蛋白
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    资源
    • 6
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL28A protein is labelled with His tag.
    原理
    Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
    产品特性
    Extracellular Domain Protein
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL28A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
    别名
    IL-28A (IL28A 产品)
    别名
    EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein
    背景
    Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IFNL2, IL28A, ZCYTO20IL-28A (Interferon-λ2, IFN-λ2), IL-28B/IFN-λ3, and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66 % amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96 % and 70 % aa sequence identity with human IL-28B and IL-29, respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
    分子量
    20.6 KDa
    UniProt
    Q8IZJ0
You are here: