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IRF5 Protein (His tag)

IRF5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455628
发货至: 中国
  • 抗原 See all IRF5 蛋白
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    蛋白类型
    Recombinant
    宿主
    • 16
    • 2
    • 1
    资源
    • 9
    • 7
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This IRF5 protein is labelled with His tag.
    原理
    Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
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    Discover our top product IRF5 蛋白
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥

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  • 限制
    仅限研究用
  • 缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 30 % Glycerol, 1 mM DTT, pH 8.0.
    储存条件
    -80 °C
    储存方法
    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    别名
    IRF5 (IRF5 产品)
    背景
    Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
    分子量
    57.1 KDa
    UniProt
    Q13568
    途径
    TLR signaling, Autophagy
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