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CD51/CD61 Protein (AA 31-988) (Biotin,His-Avi Tag)

ITGAV/ITGB3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7454142
发货至: 中国
  • 抗原 See all CD51/CD61 (ITGAV/ITGB3) 蛋白
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    蛋白类型
    Recombinant
    产品特性
    AA 31-988
    宿主
    • 4
    • 2
    • 1
    • 1
    小鼠
    资源
    • 8
    HEK-293 Cells
    标记
    This CD51/CD61 protein is labelled with Biotin,His-Avi Tag.
    原理
    Biotinylated Mouse Integrin alpha V beta 3 (ITGAV & ITGB3) Heterodimer Protein
    序列
    Phe31-Val988 (ITGAV) acidic tail & Glu26-Asp717 (ITGB3) basic tail
    特异性
    Uni-Prot: P43406 (ITGAV), O54890 (ITGB3)
    产品特性
    Recombinant Biotinylated Mouse Integrin alpha V beta 3 (ITGAV & ITGB3) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human Vitronectin, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 0.30μng/ml determined by ELISA. See testing image for detail.
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    Discover our top product ITGAV/ITGB3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
    别名
    Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer (ITGAV/ITGB3 产品)
    别名
    CD51 Protein, MSK8 Protein, VNRA Protein, VTNR Protein, integrin subunit alpha V Protein, ITGAV Protein
    背景
    ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
    分子量
    108.77 kDa(ITGAV)&80.84 kDa(ITGB3). Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.
    UniProt
    P43406
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