Aggrecan Protein (ACAN) (AA 17-721) (His tag)
ACAN
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 抗原 See all Aggrecan (ACAN) 蛋白
- Aggrecan (ACAN)
- 蛋白类型
- Recombinant
- 产品特性
- AA 17-721
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Aggrecan protein is labelled with His tag.
- 原理
- Human Aggrecan Protein
- 序列
- Ala17-Leu721
- 产品特性
- Recombinant Human Aggrecan Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala17-Leu721.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ACAN 蛋白
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Aggrecan (ACAN) (AA 1-721) protein (GST tag)
ACAN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Aggrecan (ACAN) (AA 56-155) protein (GST tag)ACAN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Aggrecan (ACAN)
- 别名
- Aggrecan (ACAN 产品)
- 别名
- AGC1 Protein, AGCAN Protein, CSPG1 Protein, CSPGCP Protein, MSK16 Protein, SEDK Protein, Agc Protein, Agc1 Protein, Cspg1 Protein, b2b183Clo Protein, cmd Protein, aggrecan Protein, aggrecan core protein Protein, ACAN Protein, Acan Protein, LOC100380783 Protein, AGC Protein
- 背景
- Aggrecan is a large proteoglycan that forms giant hydrated aggregates with hyaluronan in the extracellular matrix (ECM). The extraordinary resistance of these aggregates to compression explains their abundance in articular cartilage of joints where they ensure adequate load-bearing. In the brain, they provide mechanical buffering and contribute to formation of perineuronal nets, which regulate synaptic plasticity. Aggrecan is also present in cardiac jelly, developing heart valves, and blood vessels during cardiovascular development. Whereas aggrecan is essential for skeletal development, its function in the developing cardiovascular system remains to be fully elucidated.
- 分子量
- 78.86 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.
- UniProt
- Q6PID9
- 途径
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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