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IgG1 Protein (Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant) (His tag)

宿主: 人 宿主: HEK-293 Cells Recombinant 95,00 %
产品编号 ABIN7447926
发货至: 中国
  • 抗原 See all IgG1 蛋白
    IgG1
    蛋白类型
    Recombinant
    产品特性
    Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant
    宿主
    • 7
    • 4
    • 2
    • 1
    资源
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This IgG1 protein is labelled with His tag.
    原理
    Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag
    序列
    Glu 99 - Lys 330
    产品特性
    Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F).
    纯度
    95,00 %
    内毒素水平
    1.0 EU per μg
    Top Product
    Discover our top product IgG1 蛋白
  • 说明

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    IgG1
    Abstract
    IgG1 产品
    别名
    IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein
    物质类
    Antibody
    背景
    Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
    分子量
    28.1 kDa
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