HSV-2 gE Protein (His tag)
MALS verified
HSV2 gE
宿主: Herpes simplex virus type 2
宿主: HEK-293 Cells
Recombinant
90,00 %
-
- 抗原 See all HSV-2 gE (HSV2 gE) products
- HSV-2 gE (HSV2 gE) (Herpes Simplex Virus Type 2, Glycoprotein E (HSV2 gE))
- 蛋白类型
- Recombinant
- 宿主
- Herpes simplex virus type 2
- 资源
- HEK-293 Cells
- 标记
- This HSV-2 gE protein is labelled with His tag.
- 原理
- HSV-2 (HG52) Glycoprotein E Protein, His Tag (MALS verified)
- 序列
- Ala 21 - Arg 414
- 产品特性
- HSV-2 (HG52) Glycoprotein E, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Arg 414 (Accession # P89475).
- 纯度
- 90,00 %
- 内毒素水平
- 1.0 EU per μg
- 质量等级
- MALS verified
-
- 说明
-
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.0 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
-
- 抗原
- HSV-2 gE (HSV2 gE) (Herpes Simplex Virus Type 2, Glycoprotein E (HSV2 gE))
- 别名
- HSV-2 Glycoprotein E (HSV2 gE 产品)
- 物质类
- Viral Protein
- 背景
- Synonyms:Glycoprotein E (HSV-2),Description:Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.
- 分子量
- 45.0 kDa
-
You are here:
