CEACAM6 Protein (Fc Tag)
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- 抗原 See all CEACAM6 蛋白
- CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CEACAM6 protein is labelled with Fc Tag.
- 原理
- Human CEACAM-6 / CD66c Protein, Fc Tag (MALS verified)
- 序列
- Lys 35 - Gly 320
- 产品特性
- Human CEACAM-6, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Gly 320 (Accession # P40199-1).
- 纯度
- 95,00 %
- 内毒素水平
- 1.0 EU per μg
- 质量等级
- MALS verified
- Top Product
- Discover our top product CEACAM6 蛋白
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- 说明
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This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.7 kDa. The protein migrates as 75-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
- 别名
- CEACAM-6 (CEACAM6 产品)
- 别名
- CD66c Protein, CEAL Protein, NCA Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, carcinoembryonic antigen related cell adhesion molecule 6 Protein, Ceacam6 Protein, CEACAM6 Protein
- 背景
- Synonyms:CEACAM6,CD66c,CEAL,NCA,Description:Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
- 分子量
- 57.7 kDa
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