C5A Protein (His tag)
Quick Overview for C5A Protein (His tag) (ABIN7447911)
抗原
See all C5A (C5a) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This C5A protein is labelled with His tag.
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原理
- Cynomolgus Complement C5a Protein, His Tag
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序列
- Met 678 - Arg 751
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产品特性
- Cynomolgus Complement C5a, His Tag is expressed from E.coli cells. It contains AA Met 678 - Arg 751 (Accession # XP_015292262.2).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- C5A (C5a) (Complement Component 5a (C5a))
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别名
- Complement C5a
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背景
- Synonyms:C5a,Complement Component 5a,Description:Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
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分子量
- 10.5 kDa
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NCBI登录号
- XP_015292262
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途径
- Complement System, Carbohydrate Homeostasis
抗原
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