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SIRPG Protein (AA 29-360) (His-Avi Tag)

SIRPG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275658
发货至: 中国
  • 抗原 See all SIRPG 蛋白
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    蛋白类型
    Recombinant
    产品特性
    AA 29-360
    宿主
    资源
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This SIRPG protein is labelled with His-Avi Tag.
    原理
    Human SIRP Gamma/CD172g Protein
    序列
    Glu29-Pro360
    产品特性
    Recombinant Human SIRP Gamma/CD172g Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu29-Pro360.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human SIRP Gamma, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SIRP alpha Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    别名
    SIRP Gamma (SIRPG 产品)
    别名
    CD172g Protein, SIRP-B2 Protein, SIRPB2 Protein, SIRPgamma Protein, bA77C3.1 Protein, SIRPG Protein, signal regulatory protein gamma Protein, signal-regulatory protein gamma Protein, SIRPG Protein, LOC716034 Protein, LOC102138723 Protein
    背景
    Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
    分子量
    39.7 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9P1W8
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