DC-SIGN/CD209 Protein (AA 59-404) (His tag)
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- 抗原 See all DC-SIGN/CD209 (CD209) 蛋白
- DC-SIGN/CD209 (CD209) (CD209)
- 蛋白类型
- Recombinant
- 产品特性
- AA 59-404
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DC-SIGN/CD209 protein is labelled with His tag.
- 原理
- Human CD209/DC-SIGN Protein
- 序列
- Gln59-Ala404
- 产品特性
- Recombinant Human CD209/DC-SIGN Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln59-Ala404.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- CD209 (CD209 产品)
- 别名
- CDSIGN Protein, CLEC4L Protein, DC-SIGN Protein, DC-SIGN1 Protein, cd209 Protein, CLEC4M Protein, si:ch211-224h1.3 Protein, CD209 Protein, CIRE Protein, Dcsign Protein, SIGN-R1 Protein, SIGNR5 Protein, Cd209 Protein, CD209 molecule Protein, CD209a antigen Protein, CD209 antigen-like protein D Protein, CD209c molecule Protein, CD209 antigen Protein, CD209 Protein, cd209 Protein, Cd209a Protein, LOC100529184 Protein, Cd209c Protein, LOC100460708 Protein, LOC105484282 Protein
- 背景
- C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as SARS, SARS-CoV-2, bacteria, fungi and parasites. Pathogens exploit CD209 family proteins to promote infection and evade the immune recognition system.
- 分子量
- 40.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
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