SEZ6 Protein (AA 20-925) (His tag)
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- 抗原 See all SEZ6 蛋白
- SEZ6 (Seizure Related 6 Homolog (SEZ6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-925
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SEZ6 protein is labelled with His tag.
- 原理
- Human SEZ6 Protein
- 序列
- Leu20-His925
- 产品特性
- Recombinant Human SEZ6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His925.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human SEZ6, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 13.2ng/ml determined by ELISA. See testing image for detail.
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Seizure Related 6 Homolog (SEZ6) (AA 20-927) protein (His tag)
SEZ6 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Seizure Related 6 Homolog (SEZ6) (AA 20-922) protein (His tag)SEZ6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Seizure Related 6 Homolog (SEZ6) (AA 20-925) protein (His tag)Crystallography grade SEZ6 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Seizure Related 6 Homolog (SEZ6) (AA 20-922) protein (His tag)Crystallography grade SEZ6 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Seizure Related 6 Homolog (SEZ6) (AA 20-994) protein (rho-1D4 tag)Crystallography grade SEZ6 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Seizure Related 6 Homolog (SEZ6) (AA 20-991) protein (rho-1D4 tag)Crystallography grade SEZ6 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Seizure Related 6 Homolog (SEZ6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SEZ6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SEZ6 (Seizure Related 6 Homolog (SEZ6))
- 别名
- SEZ6 (SEZ6 产品)
- 别名
- BSRP-C Protein, D11Bhm177e Protein, mKIAA4158 Protein, sez-6 Protein, seizure related gene 6 Protein, seizure related 6 homolog Protein, Sez6 Protein, SEZ6 Protein
- 背景
- Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
- 分子量
- 98.9 kDa. Due to glycosylation, the protein migrates to 145-150 kDa based on Tris-Bis PAGE result.
- 途径
- Synaptic Membrane
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