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PLVAP Protein (AA 49-442) (His tag)

PLVAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7275502
发货至: 中国
  • 抗原 See all PLVAP 蛋白
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    蛋白类型
    Recombinant
    产品特性
    AA 49-442
    宿主
    • 5
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This PLVAP protein is labelled with His tag.
    原理
    Human PLVAP Protein
    序列
    Tyr49-Gly442
    产品特性
    Recombinant Human PLVAP Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr49-Gly442.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    别名
    PLVAP (PLVAP 产品)
    别名
    MECA32 Protein, Pv1 Protein, FELS Protein, PV-1 Protein, PV1 Protein, gp68 Protein, plasmalemma vesicle associated protein Protein, Plvap Protein, PLVAP Protein
    背景
    Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier, however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases.
    分子量
    45.97 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9BX97
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