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Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)

MSMP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275496
发货至: 中国
  • 抗原 See all Microseminoprotein, Prostate Associated (MSMP) 蛋白
    Microseminoprotein, Prostate Associated (MSMP)
    蛋白类型
    Recombinant
    产品特性
    AA 37-139
    宿主
    • 3
    • 1
    小鼠
    资源
    • 2
    • 2
    HEK-293 Cells
    标记
    Fc Tag
    原理
    Mouse PSMP Protein
    序列
    Lys37-Ser139
    产品特性
    Recombinant Mouse PSMP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Microseminoprotein, Prostate Associated (MSMP)
    别名
    PSMP (MSMP 产品)
    别名
    PSMP Protein, OTTMUSG00000007017 Protein, Psmp Protein, microseminoprotein, prostate associated Protein, MSMP Protein, Msmp Protein
    背景
    PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
    分子量
    37.9 kDa. Due to glycosylation, the protein migrates to 48-51 kDa based on Tris-Bis PAGE result.
    UniProt
    B1AWI6
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