PD-1 Protein (AA 25-167) (Fc Tag)
Quick Overview for PD-1 Protein (AA 25-167) (Fc Tag) (ABIN7275419)
抗原
See all PD-1 (PDCD1) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 25-167
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标记
- This PD-1 protein is labelled with Fc Tag.
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原理
- Human PD-1/PDCD1 Protein
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序列
- Leu25-Gln167
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产品特性
- Recombinant Human PD-1/PDCD1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu25-Gln167.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human PD-1, hFc Tag at 0.5μg/ml (100μl/Well). Dose response curve for Biotinylated Anti-PD-1 Ab., hFc Tag with the EC50 of 31.2ng/ml determined by ELISA. The affinity constant of 0.344 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (His tag)
PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (mFc Tag)PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 21-167) protein (Fc Tag)PDCD1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (Fc-Avi Tag,Biotin)PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (His-Avi Tag,Biotin)PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (Fc-His Tag)PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Programmed Cell Death 1 (PDCD1) (AA 24-170) protein (mFc-His Tag)PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (Fc Tag)PDCD1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) protein (Fc Tag,Biotin)PDCD1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 (PDCD1) (AA 25-167) (Active) protein (His tag)HPLC verified PDCD1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- PD-1
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背景
- Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
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分子量
- 42.6 kDa. Due to glycosylation, the protein migrates to 65-72 kDa based on Tris-Bis PAGE result.
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UniProt
- Q15116-1
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途径
- Cancer Immune Checkpoints
抗原
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