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Reticulon 4 Protein (RTN4) (AA 27-447) (His tag)

RTN4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275359
发货至: 中国
  • 抗原 See all Reticulon 4 (RTN4) 蛋白
    Reticulon 4 (RTN4)
    蛋白类型
    Recombinant
    产品特性
    AA 27-447
    宿主
    • 10
    • 4
    • 1
    • 1
    资源
    • 4
    • 4
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This Reticulon 4 protein is labelled with His tag.
    原理
    Human NOGOR Protein
    序列
    Cys27-Ser447
    产品特性
    Recombinant Human NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human NOGOR, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 9ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Reticulon 4 (RTN4)
    别名
    NOGOR (RTN4 产品)
    别名
    ASY Protein, NI220/250 Protein, NOGO Protein, NOGO-A Protein, NOGOC Protein, NSP Protein, NSP-CL Protein, Nbla00271 Protein, Nbla10545 Protein, Nogo-B Protein, Nogo-C Protein, RTN-X Protein, RTN4-A Protein, RTN4-B1 Protein, RTN4-B2 Protein, RTN4-C Protein, RTN4-Cw Protein, DKFZp459C0314 Protein, 1110020G17Rik Protein, AA407876 Protein, AA409940 Protein, AA960376 Protein, C130026I10Rik Protein, NgA Protein, Nogo-A Protein, mKIAA0886 Protein, mKIAA4153 Protein, NI-250 Protein, Nogo Protein, Vp20 Protein, r Protein, rat N Protein, rat NogoA Protein, reticulon-4 Protein, nogo Protein, rtn4 Protein, wu:fb17a02 Protein, wu:fb22f12 Protein, wu:fd61a07 Protein, zgc:92163 Protein, reticulon 4 Protein, reticulon 4a Protein, RTN4 Protein, rtn4 Protein, Rtn4 Protein, rtn4a Protein
    背景
    NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
    分子量
    46.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9BZR6
    途径
    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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