Quick Overview for NKG2A & CD94 (AA 98-244) protein (mFc Tag) (ABIN7275332)
抗原
NKG2A & CD94
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品特性
AA 98-244
标记
mFc Tag
原理
Mouse NKG2A&CD94 Protein
序列
Asn98-Ile244(NKG2A) & Ile32-Ile179(CD94)
特异性
Uni-Prot: Q9WU31 (NKG2A), O54707 (CD94)
产品特性
Recombinant Mouse NKG2A&CD94 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Asn98-Ile244(NKG2A)&Ile32-Ile179(CD94).
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
溶解方式
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
缓冲液
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
NKG2A & CD94
别名
NKG2A&CD94
背景
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
分子量
18.3 kDa (CD94) and 43.1 kDa (NKG2A). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.