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NKG2A & CD94 (AA 113-233), (AA 57-179) (Active) protein (Fc Tag,AVI tag,Biotin)

This Recombinant NKG2A & CD94 protein is expressed in HEK-293 Cells.
产品编号 ABIN6973173
发货至: 中国
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Quick Overview for NKG2A & CD94 (AA 113-233), (AA 57-179) (Active) protein (Fc Tag,AVI tag,Biotin) (ABIN6973173)

抗原

NKG2A & CD94

蛋白类型

Recombinant

生物活性

Active

宿主

  • 8
  • 3
  • 3

资源

  • 13
  • 1
HEK-293 Cells

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    AA 113-233, AA 57-179

    标记

    Fc Tag,AVI tag,Biotin

    特异性

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

    产品特性

    Biotinylated Human NKG2A&CD94 Protein, Fc,Avitag™

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C
  • 抗原

    NKG2A & CD94

    Sub Type

    Cocktail

    背景

    CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

    分子量

    40.4 kDa & 42.3 kDa
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