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Lrig1 Protein (AA 34-792) (His tag)

Lrig1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7275204
发货至: 中国
  • 抗原 See all Lrig1 蛋白
    Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
    蛋白类型
    Recombinant
    产品特性
    AA 34-792
    宿主
    • 6
    • 4
    Cynomolgus
    资源
    • 6
    • 3
    • 1
    HEK-293 Cells
    标记
    This Lrig1 protein is labelled with His tag.
    原理
    Cynomolgus LRIG1 Protein
    序列
    Ala34-Thr792
    产品特性
    Recombinant Cynomolgus LRIG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala34-Thr792.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus LRIG1, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product Lrig1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
    别名
    LRIG1 (Lrig1 产品)
    别名
    LIG-1 Protein, LIG1 Protein, D6Bwg0781e Protein, Img Protein, leucine rich repeats and immunoglobulin like domains 1 Protein, leucine-rich repeats and immunoglobulin-like domains 1 Protein, LRIG1 Protein, Lrig1 Protein
    背景
    The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, which are associated with a certain rate of response to targeted therapies, are ubiquitously found in human non-small cell lung cancer (NSCLC). LRIG1 was an independent prognostic factor for OS of NSCLC patients. LRIG1 in combination with other clinicopathological risk factors was a stronger prognostic model than clinicopathological risk factors alone.
    分子量
    84.16 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5V8J9
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