KLRG1 Protein (AA 60-195) (Fc Tag)
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- 抗原 See all KLRG1 蛋白
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 60-195
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KLRG1 protein is labelled with Fc Tag.
- 原理
- Human KLRG1 Protein
- 序列
- Leu60-Phe195
- 产品特性
- Recombinant Human KLRG1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Leu60-Phe195.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human KLRG1, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-KLRG1 Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. See testing image for detail.
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Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 57-188) protein (Fc Tag)
KLRG1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) protein (His tag)KLRG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 60-195) protein (His-IF2DI Tag)KLRG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-189) protein (GST tag)KLRG1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 57-119) protein (GST tag)KLRG1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-195) protein (Strep Tag)Crystallography grade KLRG1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-188) protein (Strep Tag)Crystallography grade KLRG1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 60-195) protein (His tag)Crystallography grade KLRG1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 57-188) protein (His tag)Crystallography grade KLRG1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- 别名
- KLRG1 (KLRG1 产品)
- 别名
- KLRG1 Protein, 2F1-Ag Protein, MAFA Protein, MAFA-L Protein, 2F1 Protein, CLEC15A Protein, MAFA-2F1 Protein, MAFA-LIKE Protein, killer cell lectin like receptor G1 Protein, killer cell lectin-like receptor subfamily G, member 1 Protein, KLRG1 Protein, Klrg1 Protein
- 背景
- Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3 effector phenotype.Lack of KLRG1 on Treg cells conferred on them a competitive advantage in the gut, but not in lymphoid organs. Hence, although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.
- 分子量
- 42.8 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
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