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IL31RA Protein (AA 20-519) (His tag)

IL31RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275018
发货至: 中国
  • 抗原 See all IL31RA 蛋白
    IL31RA (Interleukin 31 Receptor A (IL31RA))
    蛋白类型
    Recombinant
    产品特性
    AA 20-519
    宿主
    • 9
    • 5
    • 1
    • 1
    资源
    • 6
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL31RA protein is labelled with His tag.
    原理
    Human IL-31 RA Protein
    序列
    Ala20-Glu519
    产品特性
    Recombinant Human IL-31 RA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala20-Glu519.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-31 RA, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA. The affinity constant of 82.4nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL31RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL31RA (Interleukin 31 Receptor A (IL31RA))
    别名
    IL-31 RA (IL31RA 产品)
    别名
    IL31RA Protein, CRL Protein, CRL3 Protein, GLM-R Protein, GLMR Protein, GPL Protein, IL-31RA Protein, PLCA2 Protein, PRO21384 Protein, hGLM-R Protein, Glmr Protein, NR10 Protein, interleukin 31 receptor A Protein, IL31RA Protein, Il31ra Protein
    背景
    Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.
    分子量
    58.2 kDa. Due to glycosylation, the protein migrates to 90-116 kDa based on Tris-Bis PAGE result.
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