This IL17F protein is labelled with His-Avi Tag,Biotin.
序列
Arg31-Gln163
纯度
> 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
过滤
0.22 μm filtered
内毒素水平
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human IL-17 R alpha, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-17F, His Tag with the EC50 of 1.1ug/ml determined by ELISA. See testing image for detail.
IL17F
宿主: 小鼠
宿主: 人细胞
Recombinant
> 95 % as determined by SDS-PAGE
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
Cytokine ML-1, IL17F, IL-17F, IL24, IL-24, CANDF6, IL-17F, ML1,The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.
分子量
17.5 /14.9 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.