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IL7R Protein (His tag)

IL7R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
产品编号 ABIN7274964
发货至: 中国
  • 抗原 See all IL7R 蛋白
    IL7R (Interleukin 7 Receptor (IL7R))
    蛋白类型
    Recombinant
    宿主
    • 19
    • 8
    • 3
    • 1
    • 1
    • 1
    资源
    • 11
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This IL7R protein is labelled with His tag.
    序列
    Glu21-Gly236
    纯度
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 22.66 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL7R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL7R (Interleukin 7 Receptor (IL7R))
    别名
    IL-7R alpha (IL7R 产品)
    别名
    IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
    背景
    IL-17R alpha, IL7Ra, CD127, CDW127, ILRA,Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
    分子量
    25.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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