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IL20RA Protein (AA 33-253) (Fc Tag)

IL20RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7274931
发货至: 中国
  • 抗原 See all IL20RA 蛋白
    IL20RA (Interleukin 20 Receptor alpha (IL20RA))
    蛋白类型
    Recombinant
    产品特性
    AA 33-253
    宿主
    • 8
    • 4
    • 1
    小鼠
    资源
    • 5
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This IL20RA protein is labelled with Fc Tag.
    原理
    Mouse IL-20RA Protein
    序列
    Val33-Lys253
    产品特性
    Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 14.26 μM as determined in SPR assay (Biacore T200). See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL20RA (Interleukin 20 Receptor alpha (IL20RA))
    别名
    IL-20RA (IL20RA 产品)
    别名
    CRF2-8 Protein, IL-20R-alpha Protein, IL-20R1 Protein, IL-20RA Protein, E230031K19 Protein, interleukin 20 receptor subunit alpha Protein, interleukin 20 receptor, alpha Protein, IL20RA Protein, Il20ra Protein
    背景
    IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.
    分子量
    52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q6PHB0
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