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IL-13 Protein (His-Avi Tag,Biotin)

IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
产品编号 ABIN7274901
发货至: 中国
  • 抗原 See all IL-13 (IL13) 蛋白
    IL-13 (IL13) (Interleukin 13 (IL13))
    蛋白类型
    Recombinant
    宿主
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    资源
    • 28
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    HEK-293 Cells
    标记
    This IL-13 protein is labelled with His-Avi Tag,Biotin.
    序列
    Gly21-Asn132
    纯度
    > 95% as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Biotinylated Human IL-13, His Tag at 2μg/ml (100μl/well) on the streptavidin (5μg/ml) precoated plate. Dose response curve for Human IL-13Ra2, hFc Tag with the EC50 of 1.4μg/ml determined by ELISA. See testing image for detail.
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    Discover our top product IL13 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    IL-13 (IL13 产品)
    别名
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    背景
    IL13, IL-13, interleukin 13, NC30, P600, ALRH, BHR1, MGC116786, MGC116788, MGC116789,Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
    分子量
    15.3 kDa. Due to glycosylation, the protein migrates to 15 kDa and 35-45 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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