IDH1 Protein (AA 2-414) (His tag)
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- 抗原 See all IDH1 蛋白
- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-414
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IDH1 protein is labelled with His tag.
- 原理
- Human IDH1 Protein
- 序列
- Ser2-Leu414
- 产品特性
- Recombinant Human IDH1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ser2-Leu414.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 341-414) protein (His-IF2DI Tag)
IDH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) protein (His tag)IDH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) protein (GST tag)IDH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 2-414) protein (His tag)Crystallography grade IDH1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 2-414) protein (His tag)Crystallography grade IDH1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl, 1 mM DTT, 10 % Glycerol ( pH 7.5).
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
- 别名
- IDH1 (IDH1 产品)
- 别名
- IDCD Protein, IDH Protein, IDP Protein, IDPC Protein, PICD Protein, NADP-CICDH Protein, AI314845 Protein, AI788952 Protein, E030024J03Rik Protein, Id-1 Protein, Idh-1 Protein, Idpc Protein, cb876 Protein, fm90e09 Protein, im:7143416 Protein, wu:fm90e09 Protein, F23E12.180 Protein, F23E12_180 Protein, IDH-I Protein, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1 Protein, isocitrate dehydrogenase 1 Protein, isocitrate dehydrogenase I Protein, isocitrate dehydrogenase (NADP(+)) 1, cytosolic Protein, isocitrate dehydrogenase 1 (NADP+), soluble Protein, isocitrate dehydrogenase 1 (NADP+) L homeolog Protein, isocitrate dehydrogenase 1 Protein, IDH1 Protein, Idh1 Protein, idh1.L Protein, idh1 Protein
- 背景
- Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.
- 分子量
- 47.35 kDa same as Tris-Bis PAGE result.
- UniProt
- O75874
- 途径
- Warburg Effect
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