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CD42b Protein (AA 17-531) (His tag)

GP1BA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274755
发货至: 中国
  • 抗原 See all CD42b (GP1BA) 蛋白
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    蛋白类型
    Recombinant
    产品特性
    AA 17-531
    宿主
    • 7
    • 4
    资源
    • 4
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD42b protein is labelled with His tag.
    原理
    Human CD42b/GP1BA Protein
    序列
    His17-Leu531
    产品特性
    Recombinant Human CD42b/GP1BA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His17-Leu531.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CD42b, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 8.9ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    别名
    CD42b (GP1BA 产品)
    别名
    BDPLT1 Protein, BDPLT3 Protein, BSS Protein, CD42B Protein, CD42b-alpha Protein, DBPLT3 Protein, GP1B Protein, GPIbA Protein, VWDP Protein, GP1BA Protein, GPIba Protein, GPIbalpha Protein, glycoprotein Ib platelet alpha subunit Protein, glycoprotein Ib (platelet), alpha polypeptide Protein, glycoprotein 1b, alpha polypeptide Protein, GP1BA Protein, Gp1ba Protein
    背景
    Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.
    分子量
    57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Tris-Bis PAGE result.
    UniProt
    P07359
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