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Factor XI Protein (AA 19-625) (His tag)

F11 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274693
发货至: 中国
  • 抗原 See all Factor XI (F11) 蛋白
    Factor XI (F11) (Coagulation Factor XI (F11))
    蛋白类型
    Recombinant
    产品特性
    AA 19-625
    宿主
    • 7
    • 4
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 3
    • 2
    • 2
    HEK-293 Cells
    标记
    This Factor XI protein is labelled with His tag.
    原理
    Human Coagulation factor XI Protein
    序列
    Glu19-Val625
    产品特性
    Recombinant Human Coagulation factor XI Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu19-Val625.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in 25 mM HEPES, 150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Factor XI (F11) (Coagulation Factor XI (F11))
    别名
    Coagulation factor XI (F11 产品)
    别名
    FXI Protein, 1600027G01Rik Protein, AI503996 Protein, Cf11 Protein, LRRGT00086 Protein, coagulation factor XI Protein, F11 Protein, CpipJ_CPIJ000593 Protein, CpipJ_CPIJ001060 Protein, CpipJ_CPIJ002752 Protein, CpipJ_CPIJ003631 Protein, CpipJ_CPIJ004041 Protein, CpipJ_CPIJ004093 Protein
    背景
    Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.
    分子量
    69.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
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