CXCL13 Protein (AA 23-109) (Fc Tag)
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- 抗原 See all CXCL13 蛋白
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-109
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CXCL13 protein is labelled with Fc Tag.
- 原理
- Human CXCL13/BCA-1 Protein
- 序列
- Val23-Per109
- 产品特性
- Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CXCL13, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CXCL13 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 50 mM Tris,500 mM NaCl ( pH 7.4).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- 别名
- CXCL13 (CXCL13 产品)
- 别名
- 4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
- 背景
- Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
- 分子量
- 37.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- O43927
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