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M-CSF/CSF1 Protein (AA 33-190)

Name: M-CSF/CSF1 Protein (AA 33-190)
Brand: antibodies-online
SKU: ABIN7274423
Availability: OutOfStock

This Recombinant M-CSF/CSF1 protein is expressed in HEK-293 Cells.

Human M-CSF on Tris-Bis PAGE under reduced condition. (M-CSF/CSF1 Protein (AA 33-190))

SDS

SEC-HPLC

Immobilized Human M-CSF at 0. (M-CSF/CSF1 Protein (AA 33-190))

ELISA

Human M-CSF, No Tag immobilized on CM5 Chip can bind Human M-CSF R, hFc Tag with an affinity constant of 2. (M-CSF/CSF1 Protein (AA 33-190))

SPR

5 images

产品编号 ABIN7274423

发货至: 中国

Datasheet as PDF

Quick Overview for M-CSF/CSF1 Protein (AA 33-190) (ABIN7274423)

抗原

See all M-CSF/CSF1 (CSF1) 蛋白

M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

蛋白类型

Recombinant

宿主

人

资源

HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

产品特性

AA 33-190

原理

Human M-CSF/CSF-1 Protein

序列

Glu33-Asn190

产品特性

Recombinant Human M-CSF/CSF-1 Protein is expressed from HEK293 without tag.It contains Glu33-Asn190.

过滤

0.22 μm filtered

内毒素水平

Less than 0.05 EU per μg by the LAL method.

Biological Activity Comment

Immobilized Human M-CSF at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human M-CSF R, hFc Tag with the EC50 29.6ng/ml determined by ELISA. The affinity constant of 2.06 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (Fc Tag)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)
CSF1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag,Biotin)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) protein
CSF1 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) protein
CSF1 宿主: 小鼠宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) protein
CSF1 宿主: 小鼠宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (mFc Tag)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)
CSF1 宿主: 人宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active

限制

仅限研究用
状态

Lyophilized

溶解方式

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

缓冲液

Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

储存条件

-20 °C,-80 °C

储存方法

-20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

有效期

12 months
抗原

M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

别名

M-CSF

背景

CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

分子量

18.40 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.

UniProt

P09603-1

途径

RTK signaling