CLEC1A Protein (AA 74-280) (Fc Tag)
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- 抗原 See all CLEC1A 蛋白
- CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 74-280
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CLEC1A protein is labelled with Fc Tag.
- 原理
- Human CLEC-1 Protein
- 序列
- Gln74-Asp280
- 产品特性
- Recombinant Human CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln74-Asp280.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CLEC-1, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 22.1ng/ml determined by ELISA. See testing image for detail.
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C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 73-269) protein (Fc Tag)
CLEC1A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 1-280) protein (GST tag)CLEC1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 180-280) protein (GST tag)CLEC1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 1-280) protein (Strep Tag)Crystallography grade CLEC1A 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 1-269) protein (Strep Tag)Crystallography grade CLEC1A 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 74-280) protein (His tag)Crystallography grade CLEC1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
C-Type Lectin Domain Family 1, Member A (CLEC1A) (AA 73-269) protein (His tag)Crystallography grade CLEC1A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
C-Type Lectin Domain Family 1, Member A (CLEC1A) protein (Myc-DYKDDDDK Tag)CLEC1A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
- 别名
- CLEC-1 (CLEC1A 产品)
- 别名
- RGD1566110 Protein, CLEC1 Protein, 5930406N14Rik Protein, C-type lectin domain family 1, member A Protein, C-type lectin domain family 1 member A Protein, C-type lectin domain family 1, member a Protein, Clec1a Protein, CLEC1A Protein
- 背景
- C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
- 分子量
- 51.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8NC01
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