CD93 Protein (CD93) (AA 22-580) (Fc Tag)
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- 抗原 See all CD93 蛋白
- CD93
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-580
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD93 protein is labelled with Fc Tag.
- 原理
- Human CD93/C1q R1 Protein
- 序列
- Thr22-Lys580
- 产品特性
- Recombinant Human CD93/C1q R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr22-Lys580.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IGFBP-7, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 2.6μg/ml determined by ELISA. See testing image for detail.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CD93
- 别名
- CD93 (CD93 产品)
- 别名
- 6030404G09Rik Protein, AA145088 Protein, AA4.1 Protein, AW555904 Protein, C1qr1 Protein, C1qrp Protein, Ly68 Protein, C1QR1 Protein, C1qR(P) Protein, C1qRP Protein, CDw93 Protein, ECSM3 Protein, MXRA4 Protein, dJ737E23.1 Protein, C1qRp Protein, CD93 antigen Protein, CD93 molecule Protein, Cd93 Protein, CD93 Protein
- 背景
- CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
- 分子量
- 85 kDa. Due to glycosylation, the protein migrates to 115-120 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NPY3
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