Claudin 9 Protein (CLDN9) (His tag,Twin-Strep tag)
SPR verified
CLDN9
宿主: 人
宿主: Insect Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- 抗原 See all Claudin 9 (CLDN9) 蛋白
- Claudin 9 (CLDN9)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect Cells
- 标记
- This Claudin 9 protein is labelled with His tag,Twin-Strep tag.
- 原理
- Human Claudin-9 / CLDN9 Protein, His,Twin-Strep Tag (active membrane protein, SPR verified)
- 序列
- Ala 2 - Val 217
- 产品特性
- Human Claudin-9, His,Twin-Strep Tag (CL9-H5586) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Val 217 (Accession # O95484-1).
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- 质量等级
- SPR verified
- Top Product
- Discover our top product CLDN9 蛋白
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Claudin 9 (CLDN9) protein (Myc-DYKDDDDK Tag)
CLDN9 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- This protein carries a polyhistidine tag and a twin strep tag. The protein has a calculated MW of 27.9 kDa. The protein migrates as 23-24 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- Claudin 9 (CLDN9)
- 别名
- Claudin-9 / CLDN9 (CLDN9 产品)
- 别名
- CLDN9 Protein, nmf329 Protein, claudin 9 Protein, CLDN9 Protein, Cldn9 Protein
- 背景
- Synonyms:CLDN9,Description:Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus, it enables HCV entry into target cells just as efficiently as CLDN1.
- 分子量
- 27.9 kDa
- 途径
- Cell-Cell Junction Organization, Hepatitis C
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