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CD19 Protein (His tag)

This Recombinant CD19 protein is expressed in HEK-293 Cells.
产品编号 ABIN7198993
发货至: 中国

Quick Overview for CD19 Protein (His tag) (ABIN7198993)

抗原

See all CD19 蛋白
CD19 (CD19 Molecule (CD19))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This CD19 protein is labelled with His tag.

    原理

    Recombinant Human CD19/Leu-12 Protein (His Tag)

    序列

    Met 1-Lys 291

    产品特性

    A DNA sequence encoding the human CD19 (P15391) extracellular domain (Met 1-Lys 291) was expressed, with a polyhistidine tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 说明

    47 kDa

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell coreceptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19; induced by exogenous antigen; has been found cytoplasmic tail phosphorylated and bind to sIg.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; Differentiation Antigen CD19; T-Cell Surface Antigen Leu-12; CD19; CVID3

    分子量

    31.6 kDa

    UniProt

    P15391

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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