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ARHGEF5 Protein (His tag)

ARHGEF5 宿主: 人 宿主: HEK-293 Cells Recombinant > 93 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317679
发货至: 中国
  • 抗原 See all ARHGEF5 蛋白
    ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This ARHGEF5 protein is labelled with His tag.
    原理
    Recombinant Human TIM1/HACVR1 Protein (His Tag)
    序列
    Ser 21-Gly 290
    产品特性
    A DNA sequence encoding the mature form of human KIM1 extracellular domain (AAC39862.1) (Ser 21-Gly 290) was fused with a polyhistidine tag at the N-terminus.
    纯度
    > 93 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ARHGEF5 蛋白
  • 说明

    80-100 kDa

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
    别名
    TIM1 (ARHGEF5 产品)
    别名
    ARHGEF5 Protein, GEF5 Protein, P60 Protein, TIM Protein, TIM1 Protein, 2210412D05Rik Protein, AA717842 Protein, AW495314 Protein, Tim1 Protein, Rho guanine nucleotide exchange factor 5 Protein, rho guanine nucleotide exchange factor 5 Protein, Rho guanine nucleotide exchange factor (GEF) 5 Protein, ARHGEF5 Protein, LOC100414419 Protein, Arhgef5 Protein
    背景

    Background: HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

    Synonym: CD365;HACVR;HAVCR;HAVCR-1;KIM-1;KIM1;TIM;TIM-1;TIM1;TIMD-1;TIMD1

    分子量
    31.3 kDa
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