ZBTB17 Protein (His tag)
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- 抗原 See all ZBTB17 蛋白
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ZBTB17 protein is labelled with His tag.
- 原理
- Recombinant Human ZBTB17/Miz-1 Protein (His Tag)
- 序列
- Met 1-Ala188
- 产品特性
- Recombinant Human Zinc Finger and BTB Domain-Containing Protein 17 is produced by our E.coli expression system and the target gene encoding Met1-Ala188 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Zinc Finger and BTB Domain Containing 17 (ZBTB17) protein (Myc-DYKDDDDK Tag)
ZBTB17 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
- 别名
- ZBTB17/Miz-1 (ZBTB17 产品)
- 别名
- MIZ-1 Protein, ZNF151 Protein, ZNF60 Protein, pHZ-67 Protein, AA589413 Protein, Lp-1 Protein, Miz1 Protein, Zfp100 Protein, mZ13 Protein, Miz-1 Protein, zbtb17 Protein, zinc finger and BTB domain containing 17 Protein, zinc finger and BTB domain containing 17 S homeolog Protein, ZBTB17 Protein, Zbtb17 Protein, zbtb17.S Protein
- 背景
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Background: Zinc Finger and BTB Domain-Containing Protein 17 (ZBTB17) belongs to the Kruppel C2H2-type zinc finger protein family. ZBTB17 may function as a housekeeping DNA-binding protein that regulates the expression of specific genes, it has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. ZBTB17 may has growth arrest activity, probably through inhibition of cell cycle progression. ZBTB17 required for early embryonic development during gastrulation. ZBTB17 induces cell arrest at G1, an effect mediated by its activation of the gene coding for P15INK4b. This effect is blocked by Myc, which displaces transcriptional coactivators bound to ZBTB17. Although the downregulation of ZBTB17 may contribute to Myc-induced cell transformation, the de-activation of ZBTB17 is absolutely essential for Myc-induced apoptosis.
Synonym: Zinc Finger and BTB Domain-Containing Protein 17, Myc-Interacting Zinc Finger Protein 1, Miz-1, Zinc Finger Protein 151, Zinc Finger Protein 60, ZBTB17, MIZ1, ZNF151, ZNF60
- 分子量
- 22.3 kDa
- UniProt
- Q13105
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
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