WTAP Protein (GST tag)
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- 抗原 See all WTAP 蛋白
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This WTAP protein is labelled with GST tag.
- 原理
- Recombinant Human WTAP Protein (GST Tag)
- 序列
- Met 1-Arg 151
- 产品特性
- A DNA sequence encoding the human WTAP isoform 2 (Q15007-2) (Met 1-Arg 151) was fused with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product WTAP 蛋白
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Wilms Tumor 1 Associated Protein (WTAP) (AA 1-151) protein (His tag)
WTAP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Wilms Tumor 1 Associated Protein (WTAP) (AA 1-396) protein (GST tag)WTAP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 Associated Protein (WTAP) (AA 70-151) protein (GST tag)WTAP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 Associated Protein (WTAP) (AA 1-396) protein (Strep Tag)Crystallography grade WTAP 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Wilms Tumor 1 Associated Protein (WTAP) (AA 1-396) protein (Strep Tag)Crystallography grade WTAP 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Wilms Tumor 1 Associated Protein (WTAP) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)WTAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Wilms Tumor 1 Associated Protein (WTAP) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)WTAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Wilms Tumor 1 Associated Protein (WTAP) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)WTAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 0.15M NaCl, 0.5 mM GSH, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- 别名
- WTAP (WTAP 产品)
- 别名
- MGC75954 Protein, WTAP Protein, RGD1563824 Protein, wu:fi29a09 Protein, zgc:66202 Protein, 2810408K05Rik Protein, 9430038B09Rik Protein, WT1 associated protein Protein, Wilms tumor 1 associated protein Protein, wilms tumor 1 associated protein Protein, WT1 associated protein L homeolog Protein, Wilms tumour 1-associating protein Protein, wtap Protein, WTAP Protein, CpipJ_CPIJ006489 Protein, Wtap Protein, wtap.L Protein
- 背景
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Background: Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identified as a tumor suppressor for Wilms' tumor, but it is also overexpressed in a variety of cancer cells. The WTAP-WT1 axis in vascular cells suggest that WTAP is a vital and multifaceted regulator of vascular remodeling. WTAP has been suggested to function in alternative splicing, stabilization of mRNA, and cell growth. Knocking down endogenous WTAP increased Smooth muscle cells (SMCs) proliferation, because of increased DNA synthesis and G(1)/S phase transition, together with reduced apoptosis. These effects could be the result of WTAP suppressing the transcriptional activity of WT1 in SMCs. WTAP may thus also play a role in messenger RNA processing in mammalian cells, either dependent on or independent of its interaction with WT1.
Synonym: Mum2
- 分子量
- 45 kDa
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