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WDYHV1 Protein (GST tag)

WDYHV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318958
发货至: 中国
  • 抗原 See all WDYHV1 蛋白
    WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This WDYHV1 protein is labelled with GST tag.
    原理
    Recombinant Human WDYHV1/NTAQ1 Protein (GST Tag)
    序列
    Met 1-Cys205
    产品特性
    Recombinant Human Protein N-terminal glutamine amidohydrolase is produced by our E.coli expression system and the target gene encoding Met1-Cys205 is expressed with a GST tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product WDYHV1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of PBS,100 mM GSH,1 % TritonX-100,15 % Glycerol, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))
    别名
    WDYHV1/NTAQ1 (WDYHV1 产品)
    别名
    ntaq1 Protein, C8orf32 Protein, 2410187C16Rik Protein, AU014961 Protein, AW550036 Protein, Ntaq1 Protein, RGD1311362 Protein, C14H8orf32 Protein, si:rp71-45k5.3 Protein, WDYHV motif containing 1 Protein, WDYHV motif containing 1 S homeolog Protein, WDYHV1 Protein, wdyhv1.S Protein, wdyhv1 Protein, Wdyhv1 Protein
    背景

    Background: Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

    Synonym: Protein N-terminal glutamine amidohydrolase,WDYHV1,Protein NH2-terminal glutamine deamidase,N-terminal Gln amidase,Nt(Q)-amidase,C8orf32, NTAQ1

    分子量
    49.8 kDa
    UniProt
    Q96HA8
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