WFDC2 Protein (His tag)
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- 抗原 See all WFDC2 蛋白
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This WFDC2 protein is labelled with His tag.
- 原理
- Recombinant Human WFDC2/HE4 Protein (His Tag)
- 序列
- Glu31-Phe124
- 产品特性
- Recombinant Human WAP Four-Disulfide Core Domain Protein 2 is produced by our Mammalian expression system and the target gene encoding Glu31-Phe124 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product WFDC2 蛋白
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WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 28-124) protein (Fc Tag)
WFDC2 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124) protein (GST tag)WFDC2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124) protein (His tag)WFDC2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124), (full length) protein (GST tag)WFDC2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
WAP Four-Disulfide Core Domain 2 (WFDC2) (AA 31-124) protein (His tag)WFDC2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
WAP Four-Disulfide Core Domain 2 (WFDC2) protein (Myc-DYKDDDDK Tag)WFDC2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- 别名
- WFDC2/HE4 (WFDC2 产品)
- 别名
- WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein
- 背景
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Background: WAP Four-Disulfide Core Domain Protein 2 (WFDC2) is a 25 kDa secreted glycoprotein containing two WAP domains. Mature human WFDC2 is 94 amino acids (aa) in length. It contains two WAP domains that likely mediate antiprotease and/or antimicrobial activity (aa 31 - 73 and 74 - 123). There are four potential splice variants. One shows a deletion of aa 27-74, while three others show aa substitutions: 28 aa for aa 75-124, 23 aa for aa 1 - 74, and 10 aa for aa 71-124. WFDC2 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed by a wide variety of epithelial cells, including respiratory epithelium, salivary gland mucous cells, breast duct epithelium, distal tubule renal epithelium, and epididymal epithelium. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
Synonym: WAP Four-Disulfide Core Domain Protein 2, Epididymal Secretory Protein E4, Major Epididymis-Specific Protein E4, Putative Protease Inhibitor WAP5, WFDC2, HE4, WAP5
- 分子量
- 11.1 kDa
- UniProt
- Q14508
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