VWC2 Protein (His tag)
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- 抗原 See all VWC2 products
- VWC2 (Von Willebrand Factor C Domain Containing 2 (VWC2))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VWC2 protein is labelled with His tag.
- 原理
- Recombinant Human VWC2/Brorin Protein (His Tag)
- 序列
- Met 1-Met 325
- 产品特性
- A DNA sequence encoding the human VWC2 (NP_940972.2) (Met 1-Met 325) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Von Willebrand Factor C Domain Containing 2 (VWC2) (AA 28-325) protein (His tag)
VWC2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- VWC2 (Von Willebrand Factor C Domain Containing 2 (VWC2))
- 别名
- VWC2/Brorin (VWC2 产品)
- 别名
- si:dkey-4j1.1 Protein, PSST739 Protein, UNQ739 Protein, A930041G11Rik Protein, G11 Protein, cradin Protein, von Willebrand factor C domain containing 2 Protein, VWC2 Protein, vwc2 Protein, Vwc2 Protein
- 背景
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Background: Brorin; also known as brain-specific chordin-like protein; von Willebrand factor C domain-containing protein 2 and VWC2; is a secreted protein which contains two VWFC domains. VWC2 / Brorin is a BMP antagonist which may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain; the expression was detected in neurons; but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis; but not astrogenesis; in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.
Synonym: PSST739;UNQ739
- 分子量
- 34.1 kDa
- NCBI登录号
- NP_940972
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