电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

UPB1 Protein (His tag)

UPB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319223
发货至: 中国
  • 抗原 See all UPB1 蛋白
    UPB1 (Ureidopropionase, beta (UPB1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 2
    资源
    • 4
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This UPB1 protein is labelled with His tag.
    原理
    Recombinant Human BUP1 Protein (His Tag)
    序列
    Met 1-Glu384
    产品特性
    Recombinant Human beta-Ureidopropionase is produced by our E.coli expression system and the target gene encoding Met1-Glu384 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product UPB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    UPB1 (Ureidopropionase, beta (UPB1))
    别名
    BUP1 (UPB1 产品)
    别名
    MGC82230 Protein, wu:fb69e03 Protein, zgc:64020 Protein, BUP1 Protein, AI195023 Protein, Bup1 Protein, ureidopropionase, beta S homeolog Protein, beta-ureidopropionase 1 Protein, ureidopropionase, beta Protein, UreidoPropionase Beta Protein, upb1.S Protein, UPB1 Protein, upb1 Protein, upb-1 Protein, Upb1 Protein
    背景

    Background: β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid, respectively. Defects in β-Ureidopropionase are the cause of β-Ureidopropionase deficiency that is characterized by muscular hypotonia, dystonic movements, scoliosis, microcephaly and severe developmental delay.

    Synonym: Beta-Ureidopropionase, BUP-1, Beta-Alanine Synthase, N-Carbamoyl-Beta-Alanine Amidohydrolase, UPB1, BUP1

    分子量
    44.2 kDa
    UniProt
    Q9UBR1
You are here: