UBA1 Protein (GST tag,His tag)
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- 抗原 See all UBA1 蛋白
- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This UBA1 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human UBE1/UBA1 Protein (His & GST Tag)
- 序列
- Ser 2-Arg 1058
- 产品特性
- A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UBA1 蛋白
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Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 1-1058) protein (GST tag)
UBA1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 751-850) protein (GST tag)UBA1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 2-1058) protein (His tag)Crystallography grade UBA1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBA1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 7.4, 10 % glycerol, 0.5 mM GSH
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
- 别名
- UBE1/UBA1 (UBA1 产品)
- 别名
- A1S9 Protein, A1S9T Protein, A1ST Protein, AMCX1 Protein, GXP1 Protein, POC20 Protein, SMAX2 Protein, UBA1A Protein, UBE1 Protein, UBE1X Protein, DDBDRAFT_0190927 Protein, DDBDRAFT_0220497 Protein, DDB_0190927 Protein, DDB_0220497 Protein, Sbx Protein, Ube-1 Protein, Ube1x Protein, a1s9 Protein, a1s9t Protein, a1st Protein, amcx1 Protein, gxp1 Protein, poc20 Protein, smax2 Protein, uba1a Protein, ube1 Protein, ube1x Protein, uba1 Protein, uba1b Protein, ube Protein, zgc:66143 Protein, wu:fa01e08 Protein, wu:fb30f01 Protein, wu:fi21c11 Protein, wu:fj14g11 Protein, ubiquitin like modifier activating enzyme 1 Protein, ubiquitin activating enzyme E1 Protein, Ubiquitin-conjugating enzyme E1 Protein, ubiquitin-like modifier activating enzyme 1 Protein, ubiquitin-like modifier activating enzyme 1 S homeolog Protein, ubiquitin-like modifier activating enzyme 1 L homeolog Protein, UBA1 Protein, uae1 Protein, GL50803_4083 Protein, GL50803_10661 Protein, Uba1 Protein, uba1.S Protein, uba1.L Protein, uba1 Protein, ptr3 Protein
- 背景
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Background: UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Defects in UBA1 can cause spinal muscular atrophy X-linked type 2 (SMAX2), also known as X-linked lethal infantile spinal muscular atrophy, distal X-linked arthrogryposis multiplex congenita or X-linked arthrogryposis type 1 (AMCX1). Spinal muscular atrophy refers to a group of neuromuscular disorders characterized by degeneration of the anterior horn cells of the spinal cord, leading to symmetrical muscle weakness and atrophy. SMAX2 is a lethal infantile form presenting with hypotonia, areflexia, and multiple congenital contractures.
Synonym: A1S9,A1S9T,A1ST,AMCX1,CFAP124,CTD-2522E6.1,GXP1,POC20,SMAX2,UBA1A,UBE1,UBE1X
- 分子量
- 146 kDa
- NCBI登录号
- NP_003325
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