UBE2S Protein (GST tag)
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- 抗原 See all UBE2S 蛋白
- UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This UBE2S protein is labelled with GST tag.
- 原理
- Recombinant Human UBE2S Protein (GST Tag)
- 序列
- Met 1-Leu222
- 产品特性
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 S is produced by our E.coli expression system and the target gene encoding Met1-Leu222 is expressed with a GST tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UBE2S 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))
- 别名
- UBE2S (UBE2S 产品)
- 别名
- E2-EPF Protein, E2EPF Protein, EPF5 Protein, 0910001J09Rik Protein, 6720465F12Rik Protein, AA409170 Protein, RGD1564746 Protein, ube2s Protein, UBE2S Protein, DDBDRAFT_0188215 Protein, DDBDRAFT_0305006 Protein, DDB_0188215 Protein, DDB_0305006 Protein, e2-epf Protein, e2epf Protein, epf5 Protein, ube2s.1 Protein, ube2s.1-b Protein, ube2s.1-a Protein, ubiquitin conjugating enzyme E2 S Protein, ubiquitin-conjugating enzyme E2S Protein, ubiquitin-conjugating enzyme e2S, putative Protein, ubiquitin-conjugating enzyme E2 S Protein, ubiquitin conjugating enzyme E2 S S homeolog Protein, ubiquitin conjugating enzyme E2 S L homeolog Protein, UBE2S Protein, Ube2s Protein, ube2s Protein, ATEG_00324 Protein, Smp_180170 Protein, MCYG_01532 Protein, ube2s.S Protein, ube2s.L Protein
- 背景
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Background: Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
Synonym: Ubiquitin-Conjugating Enzyme E2 S, E2-EPF, Ubiquitin Carrier Protein S, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, UBE2S, E2EPF
- 分子量
- 50.1 kDa
- UniProt
- Q16763
- 途径
- Ubiquitin Proteasome Pathway
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