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UBE2C Protein (His tag)

UBE2C 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319146
发货至: 中国
  • 抗原 See all UBE2C 蛋白
    UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 3
    • 3
    • 1
    大肠杆菌(E. Coli)
    标记
    This UBE2C protein is labelled with His tag.
    原理
    Recombinant Human UBE2C Protein (His Tag)
    序列
    Met 1-Pro179
    产品特性
    Recombinant Human Ubiquitin-Conjugating Enzyme E2 C is produced by our E.coli expression system and the target gene encoding Met1-Pro179 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product UBE2C 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
    别名
    UBE2C (UBE2C 产品)
    别名
    LOC458287 Protein, UBCH10 Protein, dJ447F3.2 Protein, 1110015A16Rik Protein, D2Ertd695e Protein, im:7137135 Protein, zgc:123190 Protein, ubiquitin conjugating enzyme E2 C Protein, ubiquitin-conjugating enzyme E2C Protein, ubiquitin conjugating enzyme E2 C L homeolog Protein, ubiquitin conjugating enzyme E2 C S homeolog Protein, UBE2C Protein, NAEGRDRAFT_82946 Protein, ube2c.L Protein, Ube2c Protein, ube2c.S Protein, ube2c Protein
    背景

    Background: Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).

    Synonym: Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10

    分子量
    23.3 kDa
    UniProt
    O00762
    途径
    Ubiquitin Proteasome Pathway
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